The Impact Of Hospital Smoking Ban On Clozapine And Norclozapine Levels

The Impact Of Hospital Smoking Ban On Clozapine And Norclozapine Levels. Hospital under 250 beds hospital over 250 beds eldercare or hospice facility psychiatric or rehabilitative facility private practice group practice corporation readers of this article also read. Conversely, clozapine levels can decrease secondary to the induction of cytochrome p450 isoenzymes by cigarette smoke hydrocarbons.

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Irene cormac, sandra creasey, ann mcneill, michael ferriter, bernard huckstep, karen d'silva, impact of a total smoking ban in a high secure hospital, the. Patients who are smokers and on clozapine and decide to. A retrospective review of plasma clozapine and norclozapine concentrations taken from inpatients at the centre for addiction and mental health, toronto, from 2001 to 2007 was conducted.

Measuring clozapine plasma levels may be helpful in certain situations, e.g.

Levels should be a steady state, trough level. 40 year old patient with history of schizophrenia stabilized on clozapine. By investigating differences in clozapine blood levels in smoking and non‐smoking patients on clozapine, we aim to provide guidance for clinicians. There was no change in the amount of tobacco patients.